ERT for Menopausal Women With History of Breast Cancer

Women with a history of breast cancer have been advised to avoid estrogen replacement therapy (ERT). A reassessment of this approach has been initiated by several authors and clinical reports to date have not supported this tenet. The only prospective randomized trial reported to date is that of Vassilopoulou-Sellin et al. The authors conducted a […]

Breast Cancer and Hormone Replacement Therapy

Recent findings from a large observational study conducted in Great Britain show that current use – but not past use- of postmenopausal therapy is associated with an increased risk of breast cancer as well as an increased incidence of breast cancer fatalities. This large cohort study1 confirms the findings from the Women’s Health Initiative (WHI) […]

Skepticism about Hormone Replacement Therapy

In 1993 in an article in Science a group of researchers recommended caution regarding the ever-changing practices of prescribing hormone replacement therapy (HRT). In Britain the so-called Disablement Association of Hillingdon has begun a campaign to increase skepticism about the magical effects of exogenous estrogen, especially in view of heightened susceptibility to thrombo-embolic disorders and […]

Natural vs. Synthetic Estrogenes

Our culture, which sees happiness as something you put in your mouth or inject into your body, no sooner suspected that estrogen, like serotonin, was a magic philter that would restore and maintain equilibrium, health and well-being, than it began clamoring for more and more of it. Synthetic versions were swiftly patented, manufactured and sold. […]

Hormones and Estrogen-Dependent Diseases

In an article in Brainwork J. Kinoshita speculated in the kind of way that inspires drug houses to finance the running of large-scale clinical trials, in this case of the effects of estrogen given in the post menopausal age on the incidence of Alzheimer’s disease. Elderly women are more prone than men to Alzheimer’s, but […]