Risk of Breast Cancer with Combined EPT

Baseline incidence of invasive breast cancers in non-HRT users is 32/1000 between ages 50 and 65 years. Baseline incidence of endometrial cancers in non-HRT users is 5/1000 between ages 50 and 64 years. The excess risk of breast cancer with long-term use (10 years) of 19/1000 EPT and 5/1000 for ET alone can be compared […]

Hormones and Postmenopausal Health

Menopause-related estrogen loss is associated with symptoms that can have a negative impact on a woman’s sense of well-being and her daily activities. In addition, menopausal women are at an increased risk for developing osteoporosis. Therefore, for some menopausal women, hormone therapy (HT, administered as either unopposed estrogen or estrogen plus progestin) may be a […]

Skepticism about Hormone Replacement Therapy

In 1993 in an article in Science a group of researchers recommended caution regarding the ever-changing practices of prescribing hormone replacement therapy (HRT). In Britain the so-called Disablement Association of Hillingdon has begun a campaign to increase skepticism about the magical effects of exogenous estrogen, especially in view of heightened susceptibility to thrombo-embolic disorders and […]

Natural vs. Synthetic Estrogenes

Our culture, which sees happiness as something you put in your mouth or inject into your body, no sooner suspected that estrogen, like serotonin, was a magic philter that would restore and maintain equilibrium, health and well-being, than it began clamoring for more and more of it. Synthetic versions were swiftly patented, manufactured and sold. […]