Hormone Therapy and Osteoporosis

The effects of estrogen deficiency on the skeletal system have been clearly established for more than 60 years. The molecular mechanisms accounting for estrogen-related bone loss have been known for a decade or longer, and the benefits of estrogen on the skeleton have been recognized for half a century. The adverse consequences of estrogen depletion […]

Skepticism about Hormone Replacement Therapy

In 1993 in an article in Science a group of researchers recommended caution regarding the ever-changing practices of prescribing hormone replacement therapy (HRT). In Britain the so-called Disablement Association of Hillingdon has begun a campaign to increase skepticism about the magical effects of exogenous estrogen, especially in view of heightened susceptibility to thrombo-embolic disorders and […]